MRNA/LNP Process Development Scientist

Participate in multi-disciplinary matrix teams on sophisticated projects and lead problem-solving and lessons-learned activities.
Design and implement experimental plans, analyze in-process data and write and review high-quality reports.
Develop strong customer relationships through technical interactions.
Lead activities in the area of mRNA /LNP expertise.
Provide solutions to identify process risks, issues, and problems.
Contribute to improving departmental processes and implementing innovative technologies.
Demonstrate flexibility to support activities within the department.
QualificationsA Master’s Degree in life science, Chemical, Biological, or Process Engineering, or equivalent experience, with 5+ years of confirmed experience in the Biopharmaceutical industry, preferably in a PD role.
Alternatively, a PhD in Biochemistry, Chemistry, Chemical Engineering, Biological Engineering, or related scientific subject areas, or equivalent experience, with +2 years of relevant post-doctoral or industrial experience.
Key Requirements Experience with biomolecule purification techniques such as HPLC/FPLC chromatography (including affinity, ion exchange, hydrophobic interactions, and size exclusion), tangential flow filtration (TFF), and other filtration techniques.
Knowledge of technology transfer and GMP manufacturing.
Implementation of DoE studies & high-throughput screening for purification processes.
Understanding in vitro transcription (IVT) critical process parameters, reaction optimization, and scale-up.
Experience in manufacturing large mRNA molecules, including self-amplifying and circular RN As.
Understanding the mRNA-LNP encapsulation process scale-up and execution of relevant associated analytical methods.
Proven track record of efficiently working in a fast-paced and multifaceted environment.
Thermo Fisher Scientific is an Equal Opportunity Employer.
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